Regenerative Potential of Endometrial Stem Cells: A Mini Review

نویسندگان

  • Farnaz Ghobadi
  • Davood Mehrabani
  • Golnoush Mehrabani
چکیده

Recent findings in stem cell biology have opened a new window in regenerative medicine. The endometrium possesses mesenchymal stem cells (MSCs) called endometrial stem cells (EnSCs) having specific regenerative properties linked to adult stem cells. They contribute in tissue remodeling and engineering and were shown to have immuno-modulating effects. Many clinical trials were undertaken to ascertain the therapeutic potential of EnSCS. In this mini review, we showed that EnSCs are readily available sources of adult stem cells in the uterus that can be highlighted for their renewable multipotent and differentiation properties. This cell population may be a practical solution of choice in reproductive biology, regenerative medicine and autologous stem cell therapy.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Regenerative Potential of Endometrial Stem Cells: A Mini Review

Recent findings in stem cell biology have opened a new window in regenerative medicine. The endometrium possesses mesenchymal stem cells (MSCs) called endometrial stem cells (EnSCs) having specific regenerative properties linked to adult stem cells. They contribute in tissue remodeling and engineering and were shown to have immuno-modulating effects. Many clinical trials were undertaken to asce...

متن کامل

Adipose-Derived Stem Cells (ADSC) and Aesthetic Medicine: A Mini Review

In cell therapy and regenerative medicine, a reliable source of stem cells together with cytokine growth factors and biomaterial scaffolds seem necessary. As adipose tissue is easy accessible and is abundant source of adult stem cells and can differentiate along multiple lineages, it can be considered as a good candidate in aesthetic medicine. The clinical application of adipose-derived stem ce...

متن کامل

Extracellular Vesicles in Regenerative Medicine, a Brief Review

Extracellular vesicles were initially known as cellular waste carriers, while recent studies demonstrate that extracellular vesicles play important biological roles in all aspects of life-from single cells to mammalians. Their pathophysiological roles in some diseases like cancer are being decoded. Extracellular vesicles are divided into some classes and there are different strategies to isolat...

متن کامل

Bio-printing Damaged Tissues: A Novel Approach in Regenerative Medicine

Regenerative medicine, deals with functional reconstruction of damaged tissues or organs after severe injuries chronic diseases, while body's natural responses are not sufficient. In this field, stem cells due to their exclusive potential in self-renewal and differentiation into other cell types, are the main sources of functional cells in regenerative medicine. However, challenges in stem cell...

متن کامل

Tissue Engineered Scaffolds in Regenerative Medicine

Stem cells are self-renewing cells that can be differentiated into other cell types. Conventional in vitro models for studying stem cells differentiation are usually preformed in two-dimensional (2D) cultures. The design of three-dimensional (3D) in vitro models which ideally are supposed to mimic the in vivo stem cells microenvironment is potentially useful for inducing stem cell derived tissu...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره 4  شماره 

صفحات  -

تاریخ انتشار 2015